Study Evaluating the Effect of Isonatremic Dialysis Treatment in Chronic Kidney Disease Patients on Dialysis (DISON-IRC)

University Hospital Center (CHU)

Status: Unknown

Conditions: Chronic Kidney Diseases

Treatments: Procedure: Conventional dialysis treatment; Procedure: Isonatremic dialysis treatment

Study type: Observational

Funder types: Other

Identifiers

NCT04809493

RECHMPL20_0659

Details and patient eligibility

About

Aim of this study is to evaluate, in a population of chronic kidney disease patients on dialysis (Stage 5D), the effect of treatment with isonatremic dialysis (vs conventional dialysis), during an observational period of 2 months each, on:

• control of interdialytic weight gain
• perdialytic tolerance in terms of adverse events occurring during all of the sessions of the study
• body composition and thirst measured monthly during the 4 months of follow-up.
• tolerance to treatment.

Enrollment: 120 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Chronic Kidney Disease patient on dialysis (stage 5D)
• With plasma sodium concentration between 130 and 140 mmol/L
• Anuric
• Patient dialysed with dialysis machine allowing isonatremic dialysis treatment

Exclusion criteria

• Patient with plasma sodium concentration below 130 or above 140 mmol/
• Pacemaker

Trial design

120 participants in 1 patient group

patients will be receiving conventional dialysis

Description:

Patients will be receiving conventional dialysis treatment followed by isonatremic dialysis treatment during an observational period of 2 months for each treatment

Treatment:

Procedure: Conventional dialysis treatment

Procedure: Isonatremic dialysis treatment