Study Evaluating the Effects of DVS SR and Duloxetine on the Pharmacokinetics of Desipramine in Healthy Subjects

Wyeth

Status and phase: Completed; Phase 3

Conditions: Depressive Disorder, Major; Depression; Depressive Disorder

Treatments: Drug: duloxetine; Drug: desvenlafaxine SR; Drug: desipramine

Study type: Interventional

Funder types: Industry

Identifiers

NCT00366652

3151A1-401

Details and patient eligibility

About

The purpose of this study is to evaluate the effects of multiple doses of DVS SR and duloxetine on the pharmacokinetics of a single dose of desipramine in healthy subjects.

Enrollment: 20 estimated patients

Sex: All

Ages: 18 to 55 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

1. Healthy men and women between 18 to 55 years of age.
2. Healthy as determined by the investigator on the basis of medical history and physical examination, laboratory test results, vital signs and a 12-lead electrocardiogram.
3. History of being a nonsmoker for a least 1 year.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)