Study Evaluating Two Different Sirolimus-based Immunosuppressive Regimens in Elderly Kidney Transplant Recipients

Wyeth

Status and phase: Completed; Phase 4

Conditions: Kidney Failure; Graft Rejection; Aged

Treatments: Drug: Sirolimus

Study type: Interventional

Funder types: Industry

Identifiers

NCT00254709

0468-100970

Details and patient eligibility

About

The purpose of this study is to test two different sirolimus-based immunosuppressive regimens for elderly kidney transplant recipients.

Enrollment: 66 patients

Sex: All

Ages: 60+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• End stage renal disease
• Kidney transplantation
• Both donor and recipient older than 60 years

Exclusion criteria

• Prior or concurrent transplant of any organ other than the kidney
• Current clinically significant infections

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)