Study Investigating Tooth Movements With Conventional and Computer-Aided Design/Computer-Aided Manufacturing (CAD/CAM) Supported Fixed Appliances

Charité University Medicine Berlin

Status: Unknown

Conditions: Orthodontics; Tooth Movement

Treatments: Procedure: orthodontic treatment with customized archwires; Procedure: orthodontic treatment with prefabricated archwires; Procedure: orthodontic tx w/ conventional archwires+manual adjustments

Study type: Interventional

Funder types: Other

Identifiers

NCT00871091

JO 207/4-1-4

Details and patient eligibility

About

In orthodontics, conventional fixed appliances, usually consisting of prefabricated components, require step-by-step adjustment in order to move teeth in the planned direction.

May treatment be improved with customized archwires?

Study hypotheses:

• By using CAD/CAM in planning and fabrication of customized archwires, unnecessary tooth movements can be avoided and teeth can be moved on their direct path to the intended position.
• The application of CAD/CAM improves reproducibility, efficiency, and quality of orthodontic treatment.

Enrollment: 32 estimated patients

Sex: All

Ages: 18 to 35 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• treatment of front teeth with fixed orthodontic appliances is indicated
• complete secondary dentition
• age: 18-35
• in healthy general condition
• patient is informed about study and agrees to participate

Exclusion criteria

• treatment of premolars and molars is necessary
• syndromes affecting bones and teeth
• cleft lip and palate
• inflammation or reduction (more than 50%) of periodontium
• intake of drugs affecting tooth movement and bone formation
• disturbance of bone formation
• disturbance of thyroidal function
• pregnancy
• participation in additional study affecting oral hygiene
• former therapy with ionized radiation or cytostatic drugs
• caries (active phase)
• alcohol dependency

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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32 participants in 3 patient groups

1

Experimental group

Description:

CAD/CAM group, customized archwires

Treatment:

Procedure: orthodontic treatment with customized archwires

2

Active Comparator group

Description:

prefabricated archwires (superelastic)

Treatment:

Procedure: orthodontic treatment with prefabricated archwires

3

Active Comparator group

Description:

prefabricated archwires with manual adjustments

Treatment:

Procedure: orthodontic tx w/ conventional archwires+manual adjustments