Study of 99mTc-Sestamibi SPECT/CT Imaging for the Preoperative Diagnosis of Renal Oncocytoma

Johns Hopkins University

Status: Completed

Conditions: Clinical T1 Renal Mass

Treatments: Other: Preoperative 99mTc-Sestamibi SPECT/CT

Study type: Interventional

Funder types: Other

Identifiers

NCT02160925

IRB00027784

Details and patient eligibility

About

The objective of this study is to investigate the utility of 99mTc-sestamibi SPECT/CT imaging for the diagnosis of renal oncocytomas.

Enrollment: 125 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Presence of a solid enhancing cT1 renal mass detected on cross-sectional imaging
• Scheduled to undergo surgery with either partial or radical nephrectomy
• Age ≥18 years

Exclusion criteria

• Pregnancy
• Evidence of nodal or distant metastases
• History of other malignancy with concern for renal metastasis
• Known allergy to technetium or sestamibi

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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125 participants in 1 patient group

Preoperative 99mTc-Sestamibi SPECT/CT

Experimental group

Treatment:

Other: Preoperative 99mTc-Sestamibi SPECT/CT