Study of a Cohort of Non-HIV Immunocompromised Patients With Toxoplasmosis at the Strasbourg University Hospital (TOXO)

University Hospital, Strasbourg, France

Status: Enrolling

Conditions: Cerebral Toxoplasmosis

Study type: Observational

Funder types: Other

Identifiers

NCT07299500

9375

Details and patient eligibility

About

Toxoplasmosis in HIV-positive individuals is well-studied and has a codified management protocol, which is not the case for other immunodeficiencies, except for recent recommendations in the context of hematopoietic stem cell transplantation. A description of this population is necessary to estimate the number of patients affected and to define their specific management (diagnosis, treatment, prevention).

Enrollment: 30 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult (≥18 years)
• Immunocompromised (i.e., solid organ transplant recipient, hematological malignancy, cancer patient, patient treated with immunosuppressive therapy or therapy affecting the immune system by any mechanism, hematopoietic stem cell transplant recipient, patient with an autoimmune disease or immunodeficiency, whether primary or secondary).
• At least one positive toxoplasmosis PCR test (regardless of tissue)

Exclusion criteria

• Subject who has expressed opposition to the reuse of their data for scientific research.
• HIV positive
• Congenital toxoplasmosis
• Isolated ocular toxoplasmosis in immunocompetent individuals