Study of A Special Vessel Subtype in Bone Samples From Patients With Osteoporotic and Nonosteoporotic Fracture

S

Soochow University

Status

Unknown

Conditions

Femoral Neck Fractures

Treatments

Procedure: total hip arthroplasty or proximal femoral nails

Study type

Interventional

Funder types

Other

Identifiers

NCT02750046
SencondSoochowU

Details and patient eligibility

About

RATIONALE: Collecting and storing bone samples from patients with osteoporotic and nonosteoporotic fracture to study a special vessel subtype in the laboratory may help surgeon learn more about the relationship between bone mineral density (BMD) and a special vessel subtype (type H vessel). PURPOSE: This research study is looking at changes of a special vessel subtype in bone samples from patients with osteoporotic and nonosteoporotic fracture.

Full description

OBJECTIVES: Establish type H vessel in bone specimen in patients with hip fracture. Explore the correlation of BMD and type H vessel. OUTLINE: Collect human bone specimens from patients with Osteoporotic and Nonosteoporotic Fracture. Provide a repository for storage of tissue and make these specimens available for approved projects by laboratory-based investigators. Observe the type H vessel in bone slice by immunofluorescence staining. Collect clinical data on these patients including bone mineral density. Investigate the relationship between BMD and type H vessel.

Enrollment

30 estimated patients

Sex

Female

Ages

60 to 75 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Ages Eligible for Study: 65-75 Years
  • Genders Eligible for Study: Woman
  • Accepts Healthy Volunteers: NO
  • Study Population: Female patients with hip fracture. -

Exclusion criteria

  • Malignancy or benign ovarian cysts
  • Known chronic or systemic diseases
  • Hormone therapy in the previous 3 months
  • Bone metabolism and drug therapy

Trial design

Primary purpose

Diagnostic

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Single Blind

30 participants in 2 patient groups

osteoporotic fractures
Experimental group
Description:
patients with osteoporotic fractures, including femoral neck fracture and pertrochanteric fracture. Total hip arthroplasty or proximal femoral nails was needed.
Treatment:
Procedure: total hip arthroplasty or proximal femoral nails
nonosteoporotic fractures
Sham Comparator group
Description:
patients with nonosteoporotic fractures, including femoral neck fracture and pertrochanteric fracture. Total hip arthroplasty or proximal femoral nails was needed.
Treatment:
Procedure: total hip arthroplasty or proximal femoral nails

Trial contacts and locations

1

Loading...

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2024 Veeva Systems