Study of ADAMTS-13 Activity, Von Willebrand Factor and Platelet-Monocyte Aggregation in Coronary Artery Disease (ADVANCE-PCI)

University College Cork (UCC)

Status: Terminated

Conditions: Coronary Artery Disease

Treatments: Other: Blood draws

Study type: Observational

Funder types: Other

Identifiers

NCT00905294

INFACTs 2009-001

Details and patient eligibility

About

The purpose of this research is to determine the relationship between proteins and enzymes in the blood and how they work with platelets to form blood clots in patients with coronary artery disease. The investigators hypothesize that the relationship between these factors could potentially be useful in identifying patients at higher risk for heart attacks.

Enrollment: 11 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Admission to hospital with suspected index event of Non-ST-Elevation Myocardial Infarction (NSTEMI), Unstable Angina (UA) or Stable Angina (SA)
• Planned percutaneous coronary intervention during admission

Exclusion criteria

• Recent history (< 6 months) of an acute coronary syndrome (other than current admission) or stroke
• Recent history (< 6 months) of major surgery, trauma or thromboembolic event
• Percutaneous coronary or peripheral intervention or any stent placement performed within the past 6 months
• Current evidence of infection

Trial design

11 participants in 1 patient group

coronary artery disease

Description:

Subjects with coronary artery disease undergoing percutaneous coronary intervention

Treatment:

Other: Blood draws