Study of Affective Forecasting Skills in Post-traumatic Stress Disorder (TRAUPA)

University Hospital, Lille

Status: Completed

Conditions: Post-traumatic Stress Disorder

Treatments: Behavioral: Experimental: group comparison

Study type: Observational

Funder types: Other

Identifiers

NCT05268965

2021-A01582-39 (Other Identifier)

2021_0385

Details and patient eligibility

About

Post-traumatic stress disorder (PTSD) is associated with a marked tendency to have exaggerated and persistent negative beliefs and expectations about oneself or the world . Although posttraumatic stress symptoms have been shown to be associated with a tendency to negatively anticipate the future, affective forecasting skills (i.e., the ability to predict one's own emotional reactions in response to a future event) have never been explored in PTSD . The hypothesis that the PTSD is associated with a negative affective forecasting bias, characterized by a tendency to predict more intense emotional responses to future negative events.

Enrollment: 97 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Understanding and being able to express themselves in French
• Understanding of informed consent and signature of the study participation form
• Giving informed, dated and signed consent
• Benefiting from health insurance coverage
• Normal or corrected visual and auditory acuity to achieve normality
• Group 1 : DSM-5 PTSD criteria, assessed using CAPS and PTSD Checklist for DSM-5 (PCL-5, Weathers & al., 2013)
• Group 2: PTSD Criteria A only

Exclusion criteria

Refusal of participation after clear and fair information on the study.

• Visual or auditory sensory disability to participate in the study.
• Personal history of neurological disease or current neurological disease.
• Personal history of current psychiatric disorder or psychiatric disorder (excluding PTSD in patients in the experimental group), assessed via the MINI.
• Pregnant or breastfeeding women
• Consumption of toxic substances other than tobacco and alcohol.
• Minors or adults under guardianship, under judicial protection, persons deprived of liberty.
• Groups 2 and 3: personal history of psychiatric disorder or current psychiatric disorder and taking psychotropic drugs
• Group 1: personal history of psychiatric disorders or current psychiatric disorders other than anxiety, depressive, trauma and stress-related disorders and treatment with psychotropic drugs not stabilized

Trial design

97 participants in 3 patient groups

Patients meeting DSM-5 criteria for PTSD.

Treatment:

Behavioral: Experimental: group comparison

Group 2: Healthy controls who experienced a traumatic event but did not meet DSM-5 criteria for PTSD

Treatment:

Behavioral: Experimental: group comparison

Group 3: Healthy controls who did not experience a traumatic event

Treatment:

Behavioral: Experimental: group comparison