Study of Alloknesia in Atopic Dermatitis (ALLOKNESIE)

Regional University Hospital Center (CHRU)

Status: Enrolling

Conditions: Alloknesie; Atopic Dermatosis

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT06923202

29BRC24.0355

Details and patient eligibility

About

Alloknesia is defined as pruritus (= itching) triggered by light mechanical stimuli, which are responsible for the perception of light touch under physiological conditions, but which are perceived as pruritic under pathological conditions. Alloknesia occurs mainly in the context of chronic pruritus. Consequently, patients suffering from chronic pruritus frequently perceive light touch sensations as pruritic, which can be particularly unpleasant and alter human interactions and quality of life on a daily basis. However, the epidemiology and burden of alloknesia have never been studied, whatever the cause of chronic pruritus.Atopic dermatitis is one of the main diseases causing chronic itching, and patients frequently complain of alloknesia. In this study, the investigators are studying the frequency of alloknesia in patients with atopic dermatitis and measuring the consequences of alloknesia in these patients.

Enrollment: 160 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age ≥18 years
• No opposition from the patient
• Diagnosis of atopic dermatitis more than 6 months old

Exclusion criteria

• Patients who are physically or mentally unable to complete the questionnaires.
• Patients on systemic treatment for 1 month or more
• Refusal to participate
• Patients under legal protection (guardianship, curatorship)
• Patients under court protection

Trial design

160 participants in 1 patient group

Patients with atopic dermatitis

Description:

Patients will take part in the study on a single occasion, during which they will complete the various questionnaires (Alloknesia diagnostic questionnaire, WI-NRS scale, ItchyQol questionnaire, DLQI questionnaire, HADS questionnaire, PUSH-D questionnaire, PSS (Perceived Stress Scale), Epworth questionnaire, ISS questionnaire). There will be no follow-up.