Study of Alpha-blockers Alone During Preoperative Preparation in Patients With Pheochromocytoma

Kunwu Yan,MM

Status: Completed

Conditions: Adrenal Pheochromocytoma; Hemodynamic

Treatments: Drug: Abandonment of intravenous volume expansion during preoperative preparation in patients with pheochromocytoma

Study type: Interventional

Funder types: Other

Identifiers

NCT05803330

202303-1

Details and patient eligibility

About

Study of the relationship between hemodynamic stability and preoperative intravenous rehydration in patients with pheochromocytoma

Full description

All patients were subclassified into either the hemodynamic stability group (HS group) or the hemodynamic instability group (HU group) according to whether intraoperative hemodynamic instability occurred. Differences in data between the two groups were examined, and the risk factors for intraoperative hemodynamic instability were analyzed using logistic regression.

Enrollment: 95 patients

Sex: All

Ages: 18 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Clinical diagnosis of adrenal pheochromocytoma Must be able to swallow tablets

Exclusion criteria

Bilateral or multiple pheochromocytomas. Ectopic pheochromocytoma

Trial design

Primary purpose: Supportive Care

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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95 participants in 2 patient groups

PXB combined with venous dilation group

No Intervention group

Description:

Use of PXB combined with intravenous volume expansion during preoperative preparation in patients with pheochromocytoma

PXB group

Experimental group

Description:

PXB alone during preoperative preparation in patients with pheochromocytoma

Treatment:

Drug: Abandonment of intravenous volume expansion during preoperative preparation in patients with pheochromocytoma