Study of an Essential Oil and a Delmopinol Mouthrinse Effect on Dental Plaque Accumulation Index, Gingivitis Index and on Streptococcus Mutans, Lactobacillus, Aerobic and Anaerobic Oral Bacteria Colony Counts.

Universidade de Lisboa

Status: Completed

Conditions: Dental Plaque Accumulation; Gingivitis

Treatments: Drug: Essential oils mouthrinse; Drug: Delmopinol mouthrinse

Study type: Interventional

Funder types: Other

Identifiers

NCT01236950

9/2006a

Details and patient eligibility

About

The use of mouthrinses may be of relevance as a complement to daily dental hygiene procedures, especially for patients who do not comply with a proper mechanical removal of dental plaque. Essential oils and delmopinol mouthrinses are effective to reduce dental plaque accumulation and gingivitis. Also an effect on dental bacteria can be found. The study hypothesis states that there are no differences between the mouthrinses on the reduction of gingivitis and dental plaque accumulation as well on the bacterial counts of Streptococcus mutans, Lactobacillus, aerobic and anaerobic bacteria.

Enrollment: 90 patients

Sex: All

Ages: 15+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patient at the dental hygiene clinic of Faculdade de Medicina Dentária
• Signature of consent form
• Have, at least, two quadrant with 6 teeth each
• Gingival Index at baseline less than 3
• Presence of dental plaque

Exclusion criteria

• Use of a mouthrinse
• Dental Hygiene appointment in the past 6 months
• Use of antibiotics in teh past 3 months
• Presence of extensive caries and fractures of teeth

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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90 participants in 3 patient groups

Delmopinol mouthrinse

Experimental group

Description:

Subjects use the delmopinol mouthrinse

Treatment:

Drug: Delmopinol mouthrinse

Control

No Intervention group

Description:

Subjects with no use of mouthrinse

Essential oils mouthrinse

Experimental group

Description:

Subjects using the essential oils mouthrinse

Treatment:

Drug: Essential oils mouthrinse