Study of Anemia in Chronic Kidney Disease (CKD) Among High-Risk Hypertensive and Diabetic Patients in Pakistan

Roche

Status: Completed

Conditions: Anemia, Diabetes, Kidney Disease, Chronic, Hypertension

Study type: Observational

Funder types: Industry

Identifiers

NCT02444845

ML27762

Details and patient eligibility

About

The purpose of this study is to evaluate the prevalence of CKD-related anemia at an early stage through screening of high-risk patients in Pakistan at the level of physicians, cardiologists, and diabetologists. The information gathered may serve as a foundation in formulating national guidelines for better early diagnosis and management of patients with CKD.

Enrollment: 246 patients

Sex: All

Ages: 40+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age greater than or equal to 40 years
• Known hypertension and/or diabetes for at least 3 years
• Positive dipstick test result for proteinuria

Exclusion criteria

• Known CKD
• Receiving erythropoietin
• Blood transfusion within 8 weeks
• History of acute or chronic bleeding, hemolysis, or hemoglobinopathy

Trial design

246 participants in 1 patient group

Study Population

Description:

Hypertensive and diabetic patients who meet eligibility criteria will be enrolled and evaluated for the presence of anemia secondary to CKD. The first visit will capture medical history including risk factors for CKD; laboratory assessments will be performed at the second and third visits to evaluate glomerular filtration rate (eGFR) and anemia profile, respectively. Participants who are not diagnosted with CKD based upon the second visit will not return for the third visit.