Study of Antibiotic Utilization Measures and Control of ESBLs in China

Wyeth

Status and phase: Completed; Phase 4

Conditions: ICU Patient

Treatments: Drug: Third generation cephalosporins

Study type: Interventional

Funder types: Industry

Identifiers

NCT00488813

101441

Details and patient eligibility

About

A single-center, prospective, comparative, antibiotic intervention study for patients admitted to MICU1 and MICU2

Full description

1. To determine the value of using β-lactamases inhibitors in reducing the cases of ESBL producing E. coli or K. pneumoniae colonization and infection after 12 months.
2. To compare the acquisition rates of ESBL producing E. coli or K. pneumoniae at MICU1 and MICU2 after 12 months

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All patients admitted or transferred to the ICU/burn units.
• Patients of either sex, 18 years of age or older.

Exclusion criteria

• Patient with hypersensitivity to penicillins, cephalosporins, and beta-lactamase inhibitors.

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)