Study of Association Between Digital Osteoarthritis and Lower Limb Osteoarthritis (Khoala)

Centre Hospitalier Universitaire de Nice

Status: Completed

Conditions: Digital Arthrosis

Treatments: Radiation: Hand X-rays

Study type: Interventional

Funder types: Other

Identifiers

NCT01805349

12-AOI-01

Details and patient eligibility

About

Among the risk factors for lower limb osteoarthritis, if obesity is probably the most studied, digital osteoarthritis received increasing interest in recent years. Recent publications have highlighted a link between obesity and digital osteoarthritis, but also a very probable link between digital osteoarthritis and structural progression of knee osteoarthritis. Few data including hip exist and need to be confirmed on larger scale studies. We have with "Khoala" a national multiregional cohort of symptomatic gonarthrosis and coxarthrosis representative of the general population (which is rarely the case in the literature) including X ray, clinical and biological follow-up (hips and / or knees).

Enrollment: 479 patients

Sex: All

Ages: 40 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• men or women aged 40 to 75 years
• with symptomatic osteoarthritis of the hip and / or knee (femoro-tibial), unilateral or bilateral
• with a confirmed diagnosis (criteria of the American College of Rheumatology :ACR) and Kellgren and Lawrence radiological stage ≥ 2.

Exclusion criteria

• painful hip or knee prosthesis
• osteotomy in the past

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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479 participants in 1 patient group

X-Rays

Other group

Description:

patients with digital arthrosis and hip/knee arthrosis will practice hand X-rays

Treatment:

Radiation: Hand X-rays