Study of Atelectasis by Electrical Impedance Tomography

Free University of Brussels (ULB)

Status: Enrolling

Conditions: Urologic Surgical Procedures; Gynecologic Surgical Procedures

Treatments: Other: Reverse Trend (REV TREND); Other: Recruitment maneuver (RM)

Study type: Interventional

Funder types: Other

Identifiers

NCT05713929

B4062022000256

Details and patient eligibility

About

The goal of this interventional study is to learn about the effects of different positions on the occurrence, regional distribution and reversibility of atelectasis by using a PulmoVista 500 monitor (Dräger. 23542 Lübeck), during general anesthesia with mechanical ventilation.

The main questions it aims to answer are:

• The increase in atelectasis after induction of general anesthesia in supine and Trendelenburg position compared with baseline (spontaneous breathing)
• The eventual possibility of reversal of atelectasis caused by general anesthesia and Trendelenburg position by reverse Trendelenburg position and recruitment manœuvre.

Participants will be adult, autonomous and able to express their will, undergoing elective gynecological or urological surgery in the extended Trendelenburg position.

Enrollment: 40 estimated patients

Sex: All

Ages: 18 to 99 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult subjects over eighteen years old;
• Requiring laparoscopic gynecological, urological or digestive surgery;
• Surgery requiring Trendelenburg position and tracheal intubation.

Exclusion criteria

• Emergency operation;
• Thoracic surgery;
• Pulmonary, cardiac pathology;
• Pregnant woman;
• BMI > 30;
• Comorbidities defined as an American Society of Anesthesiologists physical condition greater than 2;
• Language barrier;
• Refusal of consent.

Trial design

Primary purpose: Diagnostic

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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40 participants in 2 patient groups

Recruitment maneuver (RM) group 1

Active Comparator group

Treatment:

Other: Recruitment maneuver (RM)

Reverse Trend (REV TREND) group 2

Active Comparator group

Treatment:

Other: Reverse Trend (REV TREND)