Study of Atenolol Influence on Blood Pressure During Resistance Exercise

University of Sao Paulo

Status and phase: Completed; Phase 4

Conditions: Exercise; Blood Pressure

Treatments: Drug: atenolol

Study type: Interventional

Funder types: Other

Identifiers

NCT01030016

FAPESP-06/06356-8

Details and patient eligibility

About

The study was designed to investigate if atenolol is able to blunt blood pressure increase during resistance exercise in hypertensive subjects.

Full description

The study compared intra-arterial blood pressure responses during leg-extension resistance exercise performed to fatigue at 40, 80 and 100% of 1 RM in hypertensive patients receiving placebo (first) and atenolol (second) on a single blind manner.

Enrollment: 10 patients

Sex: All

Ages: 30 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• hypertension with blood pressure levels below 160/105 mmHg under placebo.
• age between 30 and 60 years
• nonobese

Exclusion criteria

• target organ lesion
• cardiovascular risk factor
• cardiovascular disease
• physically active

Trial design

Primary purpose: Supportive Care

Allocation: Non-Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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10 participants in 1 patient group

atenolol

Experimental group

Description:

subjects received 6 weeks of atenolol

Treatment:

Drug: atenolol