Study of Blood Samples From Patients With Ewing Sarcoma and Their Relatives (GENEWING)

Institut Curie

Status: Completed

Conditions: Sarcoma

Treatments: Other: genome-wide association study

Study type: Observational

Funder types: Other

Identifiers

NCT01210209

CLCC-IC-2009-02

EU-21064

IC 2009-02

2009-A00558-49

Details and patient eligibility

About

RATIONALE: Studying samples of blood in the laboratory from patients with cancer and their relatives may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.

PURPOSE: This research study is looking at blood samples collected from patients with Ewing sarcoma and their relatives.

Full description

OBJECTIVES:

• To identify and characterize a genetic susceptibility factor to Ewing's sarcoma by performing a Genome-Wide Association Study with as many as possible Ewing sarcoma patients.

OUTLINE: This is a multicenter study.

Blood samples are collected from patients and their relatives. Blood DNA samples are analyzed for susceptibility genes of Ewing Sarcoma.

Enrollment: 350 patients

Sex: All

Ages: Under 120 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

DISEASE CHARACTERISTICS:

• Patients with Ewing sarcoma
• Relatives of Ewing sarcoma patients

PATIENT CHARACTERISTICS:

• Patients with a fusion genes specific of Ewing Sarcoma

PRIOR CONCURRENT THERAPY:

• Not applicable