Study of Blood Samples in Patients With Breast Cancer

Centre Oscar Lambret

Status: Unknown

Conditions: Breast Cancer

Treatments: Other: laboratory biomarker analysis

Study type: Observational

Funder types: Other

Identifiers

NCT00959556

INCA-RECF0635

CDR0000633531

COL-GENEOM

COL-2007-08

COL-IDRCB-2007-A00908-45

Details and patient eligibility

About

RATIONALE: Studying the genes expressed in samples of blood from patients with cancer may help doctors identify biomarkers related to cancer. It may also help doctors predict how patients will respond to chemotherapy.

PURPOSE: This clinical trial is studying blood samples in patients with breast cancer.

Full description

OBJECTIVES:

• Identify constitutional gene variants associated with a change in response.

OUTLINE: Blood samples are collected periodically for analysis of genetic factors.

Enrollment: 900 estimated patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

DISEASE CHARACTERISTICS:

• Histologically confirmed breast carcinoma
• Received first-line chemotherapy (in neoadjuvant or metastatic setting) comprising anthracyclines and/or taxanes, including for a second primary cancer
• Patient agrees to conservative surgery
• Hormone receptor status not specified

PATIENT CHARACTERISTICS:

• Menopausal status not specified
• No contraindication for chemotherapy comprising anthracyclines and/or taxanes

PRIOR CONCURRENT THERAPY:

• See Disease Characteristics
• No prior adjuvant therapy