Study of Brain-spinal Cord Neural Connectivity in Spasticity (MOVE)

Fondation Ophtalmologique Adolphe de Rothschild

Status: Enrolling

Conditions: Spasticity, Muscle

Treatments: Other: intraoperative neuroelectrophysiological monitoring

Study type: Observational

Funder types: NETWORK

Identifiers

NCT06281223

JBR_2023_9

Details and patient eligibility

About

Little is known about the peripheral and central mechanisms of action of selective dorsal rhizotomy surgery for the treatment of spasticity. A better understanding of these mechanisms will enable us to improve the surgical procedure. This will require cortico-medullo-radiculo-muscular recordings never before performed and published in the literature, and the identification of variations in connectivity correlated with the clinic.

Enrollment: 50 estimated patients

Sex: All

Ages: 3 to 17 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients aged 3 to 17 years included
• scheduled for selective rhizotomy surgery
• Having received informed consent to participate in the study (written consent from both parents)
• Affiliated or beneficiary of a social security scheme

Exclusion criteria

• Contraindications to selective rhizotomy
• History of epilepsy
• Known neurological and/or psychiatric disorders with past and/or current medical treatment, or drug addiction
• Patient under legal protection
• Pregnant or breast-feeding women