Study of Cerebral Compliance in Neurosurgical Intensive Care Units (EC2)

Centre Hospitalier Universitaire de Saint Etienne

Status: Enrolling

Conditions: Cerebrospinal; Disorder

Treatments: Other: Therapeutic data collection; Other: IntraCranial Pression (ICP) values collection; Other: Clinical data collection

Study type: Observational

Funder types: Other

Identifiers

NCT06350656

IRBN282022/CHUSTE

Details and patient eligibility

About

Despite the massive use of intracranial pressure in neuro-resuscitation, there is still no cerebral compliance evaluation index used in current practice to guide therapy.

In treatment guidelines for intracranial hypertension, patients are placed in a prone position at about 30 degrees. Several times a day, during nursing care, patients are flattened, which corresponds to a cerebral compliance test by adding a volume of cerebrospinal fluid to the cranial box.

Full description

This study aims to analyse the shape of the different components of the intracranial pressure waves (P1, P2, and P3) when the patient is flattened to determine an index to define the level of cerebral compliance.

Enrollment: 30 estimated patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Continuous intracranial pressure monitoring
• Sedated patient on mechanical ventilation

Exclusion criteria

• Craniectomy
• Major hemodynamic failure