Study of Combination Therapy With Dimebon and Donepezil (Aricept) in Patients With Alzheimer's Disease

Medivation

Status and phase: Terminated; Phase 2

Conditions: Alzheimer's Disease

Treatments: Drug: dimebon

Study type: Interventional

Funder types: Industry

Identifiers

NCT00704782

DIM13

Details and patient eligibility

About

The purpose of this study is to assess the safety and efficacy of Dimebon in combination with donepezil (Aricept) in the treatment of Alzheimer's disease.

Enrollment: 50 patients

Sex: All

Ages: 50+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Alzheimer's disease
• On donepezil (Aricept)
• Caregiver who cares for the patient at least 5 days per week

Exclusion criteria

• Unstable medical illnesses or significant hepatic or renal disease
• Other primary psychiatric or neurological disorders

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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50 participants in 1 patient group

Dimebon

Experimental group

Description:

20 mg by mouth 3 times a day

Treatment:

Drug: dimebon