Study of Compound Nanxing Zhitong Ointment in the Treatment of Chronic Pain in Musculoskeletal System

Jiangsu Kanion Pharmaceutical

Status: Completed

Conditions: Chronic Primary Musculoskeletal Pain

Treatments: Other: Do not use any other similar proprietary medicines or traditional Chinese medicines.; Drug: Compound Nanying zhitong Ointment

Study type: Observational

Funder types: Industry

Identifiers

NCT07200362

CYZZ2038026 SU

Details and patient eligibility

About

A prospective cohort study on the treatment of chronic pain in the musculoskeletal system with Compound Nanxing Pain Relief Ointment. This study adopted an observational research design. Through a cohort study, patient medical records were collected to meet the criteria of chronic pain classification in International Classification of Diseases 11th Revision (ICD-11), which is located in the musculoskeletal system and occurs in the neck and shoulders, waist and back, limbs, and meets the diagnostic criteria of "cold syndrome" in traditional Chinese medicine. The target population was selected to evaluate the clinical effects of Compound Nanxing Pain Relief Ointment in treating chronic pain in the musculoskeletal system, reducing pain, improving muscle and bone function status, and enhancing quality of life. The study aimed to compare the heterogeneity of the clinical effects of Compound Nanxing Pain Relief Ointment in treating chronic pain in the musculoskeletal system. The study plan included 3000 patients, and no intervention in treatment and medication was provided to the patients during the observation period. The shortest medication duration was 2 weeks, and the longest observation period was 3 months.

Enrollment: 3,029 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

For those who visit the orthopedics department, rheumatology department, or pain clinic:

1. Those whose pain is located in the musculoskeletal system as classified in International Classification of Diseases 11th Revision(ICD-11) for chronic pain, and occurs in the neck, shoulders, waist, back, or limbs;
2. Those who meet the diagnostic criteria of "cold syndrome" in traditional Chinese medicine, and their chronic pain worsens or occurs when exposed to cold;
3. Those with continuous or intermittent pain lasting more than 3 months, and without surgical indications.

Exclusion criteria

None

Trial design

3,029 participants in 2 patient groups

exposed group

Description:

Use Compound Nanying zhitong Ointment alone, or use it in conjunction with conventional Western medicine treatment, without using any other similar Chinese patent medicines or traditional Chinese medicines.

Treatment:

Drug: Compound Nanying zhitong Ointment

The non-exposure group

Description:

Do not use any other similar proprietary medicines or traditional Chinese medicines.

Treatment:

Other: Do not use any other similar proprietary medicines or traditional Chinese medicines.