Study of DERMABOND ProPen in Closure of Colectomy Wounds

Singapore Health Services (SingHealth)

Status and phase

Terminated

Phase 2

Conditions

Wound

Treatments

Procedure: Dermabond ProPen (2-octylcyanoacrylate)

Procedure: Skin closure with skin staples

Study type

Interventional

Funder types

Other

Identifiers

NCT00978133

Dermabond colectomy wounds

Details and patient eligibility

About

2-octylcyanoacrylate (2-OCA) has been used extensively in clinical practice in trauma, plastic surgery, orthopaedic surgery, emergency medicine and paediatrics. Most studies on 2-OCA to date have focused on closure of short wounds, and only one has included closure of abdominal wounds in the context of general surgery. Here, the investigators will look at the results of closure of abdominal wounds in patients undergoing elective colectomies with 2-OCA, which is commercially available to us, versus closure with skin staples, which is the current standard technique of skin closure employed in the Department of Colorectal Surgery, Singapore General Hospital. The primary objective was to measure effectiveness of 2-OCA in 2 respects - the adequacy of wound healing and cosmesis, and the incidence of superficial wound infection.

Enrollment

74 patients

Sex

All

Ages

21+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Patients undergoing elective colectomies for benign or malignant conditions
Midline vertical incisions or skin crease incisions
Above the age of 21 years old
Able to make own valid informed decisions

Exclusion criteria

Patients undergoing surgery for recurrent or metastatic disease
Surgery for surgical emergencies such as acute abdomen or bleeding
Known allergy to DERMABOND ProPen Tissue Adhesive or any of its constituents (cyanoacrylate or formaldehyde)
Patients on immunosuppression