Study of Dietary Intervention Under 100 MMOL in Heart Failure (SODIUM-HF)

University of Alberta

Status

Completed

Conditions

Heart Failure

Treatments

Other: low-sodium diet (1500 mg daily)

Study type

Interventional

Funder types

Other

Identifiers

82-SH-01

Details and patient eligibility

About

This study aims to identify the relationship between a low-sodium diet and neurohormonal and clinical status in stable chronic HF patients.

Enrollment

38 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Patients will be recruited from each research center if they are 18 years or older, with confirmed diagnosis of Heart Failure (including both those with a reduced and preserved systolic function), NYHA II-IV, and willing to sign informed consent.

Exclusion criteria

Subjects will be excluded if they have severe hyponatremia (serum sodium <130 mmol/L)
Renal failure (a glomerular filtration rate < 30 mL/min)
Uncontrolled thyroid disorders
Hepatic failure
Implantable cardiac device (ICD or CRT) or myocardial revascularization procedures (coronary angioplasty and/or surgical revascularization) in the previous 3 months
Uncontrolled atrial fibrillation or recurrent ventricular arrhythmias
Malignancy, or with moderate-severe dementia.
Patients will be excluded if, in the opinion of the investigator, another condition exists that would preclude dietary compliance or compliance with the protocol.