Study of Early Versus Delayed Carotid Endarterectomy (CEA) for Small to Medium-sized Ischemic Stroke Caused by High-grade Carotid Stenosis

University of California San Diego

Status and phase: Withdrawn; Phase 1

Conditions: Stroke; Carotid Stenosis

Treatments: Procedure: carotid endarterectomy

Study type: Interventional

Funder types: Other

Identifiers

NCT00315562

UCSD IRB #060323

Details and patient eligibility

About

Pilot study of early versus delayed carotid endarterectomy (CEA) for small to medium-sized ischemic stroke caused by high-grade carotid stenosis.

Full description

Pilot study of early versus delayed carotid endarterectomy (CEA) for small to medium-sized ischemic stroke caused by high-grade carotid stenosis.

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age 18 and older.
• New small to medium-sized ischemic stroke (defined as less than 1/3 of the MCA territory) in the territory of 70% or greater carotid stenosis.
• Women of child-bearing potential will be included only if there is a negative pregnancy test and they agree to birth control during the treatment period.

Exclusion criteria

• Patients judged to be a poor surgical candidate by the treating physicians.
• Unstable neurological status.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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0 participants in 2 patient groups

Early

Experimental group

Description:

Early

Treatment:

Procedure: carotid endarterectomy

Delayed

Active Comparator group

Description:

Delayed

Treatment:

Procedure: carotid endarterectomy