Study of Effectiveness of GEMDOX in Relapsed Osteosarcoma

Azienda Ospedaliera Ospedale Infantile Regina Margherita Sant'Anna

Status: Completed

Conditions: Osteosarcoma Metastatic; Osteosarcoma Recurrent

Treatments: Other: observation

Study type: Observational

Funder types: Other

Identifiers

NCT04651179

OSTEOREC/OSS

Details and patient eligibility

About

A retrospective observational study of the effectiveness of gemcitabine - docetaxel in patients with relapsed osteosarcoma who have been treated with HD IFO in first line treatment

Enrollment: 33 patients

Sex: All

Ages: 4+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Age at diagnosis of high grade osteosarcoma >= 4

• Received first line treatment with HD IFO

• Following HD IFO treatment, they have been diagnosed refractory disease and they satisfy at least one of the following criteria :

  1. Relapsed in the first 24 month following the initial diagnosis, regardless of location and resectability
  2. Lung relapsed disease with more than 2 nodules diagnosed over 24 months from the initial diagnosis
  3. Non resectable relapsed disease diagnosed over 24 months from the initial diagnosis Before or during GEMDOX treatment, eligible patients may have been subject to metastasectomy

Exclusion Criteria: none