Study of Effects of Preoperative Oral Domperidone on Gastric Residual Volume After Clear Fluid Ingestion in Patients Scheduled for Elective Surgeries

Ain Shams University

Status and phase

Completed

Phase 3

Conditions

Gastric Residual Volume

Treatments

Drug: Domperidone

Drug: Folic acid

Study type

Interventional

Funder types

Other

Identifiers

NCT05570292

FMASU MS210/2022

Details and patient eligibility

About

General Anesthesia requires preoperative fasting according to specific instructions. Regarding Fasting Guidelines, The American Society of Anesthesiologists (ASA) recommends patients to fast from fatty food or meat eight hours prior to surgery, non-human milk or light meal for six hours prior, breast milk for four hours prior, and clear liquids including water, pulp-free juice, and tea without milk for two hours prior to the anesthetic. ASA fasting guidelines application represents the primary method to avoid aspiration as it ensures that stomach is empty before induction of anesthesia. These guidelines cannot be applied on all cases as in urgent or emergent situations or in morbidities associated with delayed gastric emptying, like Diabetes mellitus and some neurological disorders (

Enrollment

40 patients

Sex

All

Ages

18 to 65 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Patients of both sexes
aged between 18-65 years
who are categorized by ASA physical status as I or II
undergoing elective surgeries under general anesthesia

Exclusion criteria

Patients with known or suspected delayed gastric emptying (e.g. Diabetes mellitus) -psychiatric disorders
hypersensitivity to the study medications
peoples undergoing surgeries that associated with high incidence of Post operative nausea and vomiting (PONV) (e.g. Cholecystectomy, gynecological, ophthalmological, otorhinolaryngological, and laparoscopic surgeries).