Study of Efficacy and Safety of Cream Infused With HuangQin (Root of Scutellaria Baicalensis) Extract for the Reduction of Hyperpigmentation

Mae Fah Luang University

Status

Completed

Conditions

Hyperpigmentation; Melanin

Treatments

Other: Investigator developed cream infused with HuangQin extract

Study type

Interventional

Funder types

Other

Identifiers

NCT07133204

EC 24061-25

Details and patient eligibility

About

The aim of this study is to evaluate the efficacy of a topical cream infused with Scutellaria baicalensis extract in reducing hyperpigmentation on the face.

The study is experimental clinical pilot study as a single group pretest-posttest.

A ROAT is conducted 1 week prior to the experiment. Participant apply the cream on the hypigmented area daily. Facial skin parameters (i.e. melanin index, erythema index) is evaluated at week 0, 1, 2 and 4.

Enrollment

38 patients

Sex

All

Ages

30 to 60 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Male or Female
Has at least 1 hyperpigmentation spot (size > 3mm) on either side of the face
30-60 y/o
Fitzpatrick skin types II-IV
Agrees to use sunscreen SPF50+ and willing to avoid strong sunlight exposure during the study

Exclusion criteria

Pregnant or lactating
Use of whitening products or treatment within 1 month before this study
Currently using contraceptives
History of allergy to any ingredient in the intervention cream
Has skin conditions which can interfere with the measurement (i.e. severe acne, eczema, herpes simplex)
Severe disease (i.e. immunodeficiency, cancer)
Enrolled in other clinical study within 3 month before this study