Study of Epidemiologic Investigation and Mechanism of Brain Network of Otologic and Cognitive Function With Post-COVID-19

Sun Yat-sen University

Status: Completed

Conditions: COVID-19; Otological Disease; Cognitive Decline

Study type: Observational

Funder types: Other

Identifiers

NCT05787301

SYSKY-2023-151-01

Details and patient eligibility

About

The purpose of this study was to analysis the incidence of ear symptoms, cognitive function decline and emotional disorders in Chinese people who were infected with COVID-19, exploring the impact of COVID-19 on the auditory system, cognitive function and emotional function, and analyzing the changes in functional connectivity of brain network after COVID-19 infection.

Enrollment: 30 patients

Sex: All

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Confirmed cases of COVID-19 that test positive for nucleic acid or antigen
• After infection with COVID-19, the patient has experienced hearing loss, tinnitus, ear tightness, ear pain, vertigo and other ear symptoms, memory loss, depression and so on

Exclusion criteria

• Diagnosed cognitive disability
• Patients with confirmed Meniere's disease, auditory neuropathy, and heavy noise exposure
• Those with incomplete basic information or for other reasons are unable to complete questionnaires and other listening and cognitive assessments

Trial design

30 participants in 3 patient groups

Patients with hearing loss after infection

Description:

Patients with hearing loss after infection

Patients with hearing loss before infection

Description:

Patients with hearing loss before infection

Healthy control

Description:

Healthy subjects who have never been infected with COVID-19 or diagnosed with hearing loss.