Study of Eye Movements as Markers of the Physiological, Cerebral and Cognitive State of Healthy Subjects (EyeProxy)

Grenoble Alpes University Hospital Center (CHU)

Status: Completed

Conditions: Healthy

Treatments: Other: Neuroimaging

Study type: Interventional

Funder types: Other

Identifiers

NCT04325971

38RC20.063

Details and patient eligibility

About

The goal of this study is the multimodal exploration via eyetracking, MRI and EEG data of ocular movements and the corresponding brain activation during ecologic visual stimulation in the healthy population.

Full description

Cerebral activation following visual stimulation is explored using two neuroimaging techniques EEG and MRI while eye movements are recorded. Three experiments are performed: in MR scanner 1) functional localisation of specific areas: LOC, FFA, MT/V5, V1 and V2 and 2) a saccadic choice experiment; with EEG, replication of the experiments performed in the MR scanner and 3) an additional experiment of movement detection during the ocular saccades.

Thirty young volunteers (18-40 y old) are involved.

Enrollment: 45 patients

Sex: All

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Normal vision or corrected to normal
• Social security affiliation
• Signed consent to participate
• No pregnancy fo women

Exclusion criteria

• Audition and motor troubles
• Incapable to decide (Persons mentioned in L1121-5,6 et 8 of public health code)
• Neurological disorders
• Pathology affecting oculomotor control
• MRI incompatibility

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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45 participants in 1 patient group

Healthy Subjects

Experimental group

Description:

All healthy subject are gathered in one arm

Treatment:

Other: Neuroimaging