ClinicalTrials.Veeva

Menu

Study of Foam Sclerotherapy Versus Ambulatory Phlebectomy

Imperial College London logo

Imperial College London

Status and phase

Enrolling
Phase 4

Conditions

Varicose Veins

Treatments

Procedure: Ambulatory phlebectomy
Drug: Foam sclerotherapy

Study type

Interventional

Funder types

Other

Identifiers

NCT03416413
17/WS/0192

Details and patient eligibility

About

This study will be comparing the treatment of varicose vein tributaries using either foam sclerotherapy or ambulatory phlebectomies. Patients will be randomised to having either ambulatory phlebectomy (group A) or foam sclerotherapy (group B) following treatment of their saphenous vein.

The re-intervention rates, safety, patient experience as well as the cost effectiveness of each intervention will be assessed.

Enrollment

160 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Adults over 18 years of age
  • Symptomatic GSV or SSV vein reflux > 0.5 seconds on colour Duplex
  • Varicose vein tributary requiring treatment

Exclusion criteria

  • Current DVT
  • Recurrent varicose veins
  • Arterial disease (ABPI<0.8)
  • Vein diameter < 3mm
  • Preference for one of the treatment options
  • Patient who are unwilling to participate
  • Inability or unwillingness to complete questionnaires
  • Inability to attend follow-up appointments
  • Patient currently included in a study of varicose vein treatment

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Single Blind

160 participants in 2 patient groups

Ambulatory Phlebectomy
Active Comparator group
Description:
Ambulatory phlebectomy of varicose vein tributaries
Treatment:
Procedure: Ambulatory phlebectomy
Foam Sclerotherapy
Active Comparator group
Description:
Injection of foam sclerosant into varicose vein tributaries
Treatment:
Drug: Foam sclerotherapy

Trial contacts and locations

1

Loading...

Central trial contact

Amjad Belramman; Roshan Bootun

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2025 Veeva Systems