Study of Follicle Stimulating Hormone (FSH) Receptor in Women With Low Antral Follicle Count

Assistance Publique - Hôpitaux de Paris

Status: Completed

Conditions: Fertility; Antral Follicle Deficit

Treatments: Procedure: Blood samples

Study type: Observational

Funder types: Other

Identifiers

NCT00231504

P041013

CRC04140

Details and patient eligibility

About

The deficit in the total number of antral follicles is associated with a reduction of the ovarian fertility potential in young women.

The principal objective of this study is to evaluate the relationship between FSH receptor polymorphism and antral follicle count.

The investigators have designed a study of FSH receptor polymorphisms P1 and P2 as an association with a low antral follicle count in the ovary.

Full description

The present study will compare the prevalence of FSH receptor polymorphisms P1 and P2 in women having reduced follicle count (1 to 9 antral follicles) or normal follicle count (13 to 20 antral follicles) determined by ultrasound scans.

Enrollment: 82 patients

Sex: Female

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 18 to 35 years old
• 1 to 9 or 13 to 20 antral follicles
• Caucasian, occidental Europe
• Presence of both ovaries
• Informed consent

Exclusion criteria

• Ovarian anomalies
• Menopause
• Pregnancy
• Other diseases