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About
Alcoholic hepatitis carries a risk of high mortality at short term, especially in its severe form. Its diagnosis is confirmed by liver biopsy. The prevalence of alcoholic hepatitis, severe or not severe, is poorly known and prospective data are needed. The present observational study aims to define the prevalence of alcoholic hepatitis among patients admitted for jaundice and determine their outcome according to the severity. Survival and markers of liver dysfunction will be assessed. A biobank including genetic samples will be created to identify the disease profile in terms of inflammation and regeneration. The performance of non-invasive criteria for diagnosis will also be studied.
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Inclusion criteria
For SAH group:
Alcohol consumption :
Recent jaundice episode (less than 3 months)
Bilirubin> 50 mg / l (85μmol / l)
For NSAH group:
For cirrhosis (control) group:
Alcohol consumption :
Unambiguous presence of cirrhosis criteria, including:
Exclusion criteria
For NAH and NSAH groups:
For cirrhosis (control) group:
447 participants in 3 patient groups
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Central trial contact
Alexandre Louvet, MD,PhD
Data sourced from clinicaltrials.gov
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