Study of Genetic Differences in People With Depression (Genetics)

University of California, Los Angeles (UCLA)

Status: Completed

Conditions: Depressive Disorder, Major

Study type: Observational

Funder types: Other

Identifiers

NCT00229463

01-10-049

Details and patient eligibility

About

The purpose of this study is to identify genes involved in depression. Specifically, the investigators will analyze some genes that may be related to whether or not a person responds to antidepressant medication. This project is part of basic scientific research to increase understanding of the role of genetic influences in psychological and mental processes involved in the response to treatment for depression.

Enrollment: 200 estimated patients

Sex: All

Ages: 18 to 75 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• History of Unipolar Major Depression
• Control subjects must be healthy normal adults

Exclusion criteria

• Subjects with mood symptoms that are not severe enough to qualify for MDD
• Subjects with any active medical illness that may be related to ongoing mood disorder
• Normal subjects must be free from: a psychiatric diagnosis, substance abuse, a history of seizure disorder, and any serious medical illness