Study of Genotype and Phenotype in Patients With Alpha 1-Antitrypsin Deficiency

National Center for Research Resources (NCRR)

Status: Terminated

Conditions: Alpha 1-Antitrypsin Deficiency

Study type: Observational

Funder types: Other; NIH

Identifiers

NCT00005098

199/14810

WUSM-930603

Details and patient eligibility

About

OBJECTIVES:

I. Establish cell lines from patients with alpha 1-antitrypsin deficiency in order to examine genetic traits that predispose to liver injury.

Full description

PROTOCOL OUTLINE:

Patients undergo blood draw and skin biopsy. Cells are isolated from patients' blood and skin, cell lines are established, and genetic traits are examined.

Sex: All

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

• Alpha 1-antitrypsin deficiency