Study of Hemodynamic Conditions Measured During Hepatectomy (DEBIFOIE)

Regional University Hospital Center (CHRU)

Status: Completed

Conditions: Circulatory; Change; Liver Dysfunction

Treatments: Procedure: Liver debit measure

Study type: Observational

Funder types: Other

Identifiers

NCT03371537

RIPH3-RNI17/DEBIFOIE

2017-61 (Other Identifier)

2017-A01754-49 (Other Identifier)

Details and patient eligibility

About

Hepatocellular insufficiency is a dreaded complication after hepatectomy, since, if it is persistent, it leads to the death of the patient in the absence of liver transplantation.

The preoperative evaluation aims in particular to estimate the risk of postoperative hepatocellular insufficiency so as to minimize or contraindicate high-risk patients.

It has been shown that the flow of the portal vein is correlated with liver function, especially in the living donor and after portal embolization. More recently, the study of flow rates in the portal vein and the hepatic artery after transplantation has shown a correlation with the recovery of graft function.

The hypothesis is that portal and arterial flow after hepatectomy can predict postoperative hepatocellular function.

Full description

Measurements of flow rates in the portal vein and the hepatic artery by different transit times are available thanks to the Medistim VeriQTM system that the investigators already use routinely in the context of liver transplantation when performing hepatectomies.

Enrollment: 9 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patient 18 years or more
• Patient undergoing laparotomy for liver resection

Exclusion criteria

• Patient under tutorship or curatorship
• Pregnant or lactating woman
• Difficulties in understanding French
• Patient operated by laparoscopy
• Patient having objected to the processing of his data

Trial design

9 participants in 1 patient group

Hepatectomy

Description:

Patient undergoing laparotomy for liver resection. The aim is to measure the flow rates in the portal vein and the hepatic artery.

Treatment:

Procedure: Liver debit measure