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Study of Hypothalamic Metabolism in Spontaneous Cluster Headache Attacks

P

Public Assistance-Hospitals of Marseille (AP-HM)

Status

Terminated

Conditions

Cluster Headache

Treatments

Procedure: position emission transaxial tomography

Study type

Interventional

Funder types

Other

Identifiers

NCT00458770
2006/22
2009-A00149-48

Details and patient eligibility

About

Cluster headache is characterized by unilateral excruciating head pain and autonomic dysfunction. Hypothalamic overactivity was observed in nitrate-induced cluster-headache and in only one case of spontaneous cluster headache 'Sprenger et al, 2004). This prompted the application of hypothalamic deep brain stimulation. The aim of this data is to precise the localisation of the hypothalamic activation.

Enrollment

1 patient

Sex

All

Ages

18 to 65 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • cluster headache in crisis
  • no serious illnesses in progress as cancer, autoimmune disease, liver disease
  • patient without chronic psychiatric disease excluding moderate and reactional depression
  • no demential disease
  • no anxious or depressive disease
  • no contraindication to PET scan (pregnancy and breast-feeding)
  • social security cover
  • written informed consent

Exclusion criteria

  • No effective contraception taken
  • unable to realize a decubitus of 15 minutes long

Trial design

Primary purpose

Basic Science

Allocation

N/A

Interventional model

Single Group Assignment

Masking

None (Open label)

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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