Study of IGRP-specific T Cell in Peripheral Blood of Type 1 Diabetes Mellitus

Zhejiang University

Status: Completed

Conditions: Diabetes Mellitus

Treatments: Other: No intervention

Study type: Observational

Funder types: Other

Identifiers

NCT03136939

2016-420

Details and patient eligibility

About

10 type 1 diabetes, 10 type 2 diabetes and 10 healthy controls matched with age and sex were enrolled in our study and their periphera blood mononuclear cells (PBMC) were isolated. We implemented ELISPOT(Enzyme-linked Immunospot Assay) to detect the interferon-γ (IFN-γ）which secreted by IGRP-specific T cell. Results were compared between these groups.

Enrollment: 30 patients

Sex: All

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• the criteria of type 1 and type 2 diabetes

Exclusion criteria

• no diabetes

Trial design

30 participants in 3 patient groups

type 1 diabetes

Treatment:

Other: No intervention

type 2 diabetes

Treatment:

Other: No intervention

healthy people

Treatment:

Other: No intervention