Study of Imaginomics Predicting Early Surgical Rates in Crohn's Disease

Sun Yat-sen University

Status: Enrolling

Conditions: Prognostic Model; Radiomics; Crohn Disease

Treatments: Other: CTE examination

Study type: Observational

Funder types: Other

Identifiers

NCT05174208

2021-ZSLYEC-341

Details and patient eligibility

About

Crohn's disease (CD), a type of inflammatory bowel disease (IBD), is a chronic intestinal recurrent inflammatory disease involving the entire digestive tract. Most CD patients require surgery for complications, including stenosis, perforation, and severe intestinal bleeding. Predicting early-onset surgery risk is of great importance to assist launching of therapeutic strategies. We aim to establish a digital prognostic model and nomogram using radiomics, which will help clinical practice.

Enrollment: 300 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

patients with a confirmed diagnosis of CD; a follow-up more than 1 year; without previous CD-associated intestinal surgeries; complete data of CTE.

Exclusion criteria

patients without a confirmed diagnosis of CD; with incomplete data and a follow-up less than 1 year; patients have previous intestinal surgeries; patients who have never undergone CTE examination.

Trial design

300 participants in 1 patient group

CD

Treatment:

Other: CTE examination