Study of Immunity Dysfunction Induced by Extracorporeal Assistance (ECMO / ECLS) (IMPEC)

Rennes University Hospital

Status: Completed

Conditions: Acute Respiratory Distress Syndrome; Cardiogenic Shock

Treatments: Biological: Blood test

Study type: Observational

Funder types: Other

Identifiers

NCT03262155

35RC16_3037_IMPECstudy

Details and patient eligibility

About

Study of immunosuppression biomarkers in patients with ARDS or cardiogenic shock with ECMO / ECLS, compared to patients with ARDS or cardiogenic shock without ECMO / ECLS

Enrollment: 18 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient older than 18 years old
• Patient hospitalized in an intensive care unit
• Patient whose initial ARDS or Cardiogenic shock began less than 5 days before admission
• Patients hospitalized for ARDS or Cardiogenic shock with ECMO / ECLS or - Patients hospitalized for ARDS or Cardiogenic shock without ECMO / ECLS

Exclusion criteria

• Opposition of patient, relative or legal representative for participation in the study
• Pregnant woman
• Pre-immunodepression
• Implementation of immunosuppressive therapy such as chemotherapy, cyclophosphamide, high-dose corticosteroids (> 0.5mg / kg / day).

Trial design

18 participants in 2 patient groups

ECMO / ECLS

Description:

Patients hospitalized for ARDS or Cardiogenic shock with ECMO / ECLS

Treatment:

Biological: Blood test

No ECMO / ECLS

Description:

Patients hospitalized for ARDS or Cardiogenic shock without ECMO / ECLS

Treatment:

Biological: Blood test