Study of Intramural Spread Pattern in Low Rectal Cancer.

Wenzhou Medical University

Status: Completed

Conditions: Rectal Cancer Stage; Rectal Cancer Patients

Study type: Observational

Funder types: Other

Identifiers

NCT07202169

KY2025-R091

Details and patient eligibility

About

The purpose of this study is to study the law of intramural diffusion of low rectal cancer in different stages, and to explore the relationship between intramural diffusion of low rectal cancer and the distal resection margin during operation, so as to provide theoretical basis for clinicians to formulate accurate and individualized treatment plans, and help improve the prognosis and quality of life of patients.

Enrollment: 106 patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

• Inclusion criteria

  1. Patients aged 18-75 years old
  2. Pathology suggestive of moderately to highly differentiated rectal adenocarcinoma
  3. Tumor lower margin ≤ 5 cm from the anal verge
  4. No distant metastasis such as lung, liver and other organs

• exclusion criteria

  1. Preoperative patients with severe underlying diseases (such as severe liver and kidney function, cardiopulmonary function, coagulation dysfunction, etc.)
  2. Patients with malignant tumors in other parts of the body

Trial design

106 participants in 4 patient groups

Patients with T1 ultra-low rectal cancer

Patients with T2 ultra-low rectal cancer

Patients with T3 ultra-low rectal cancer

Patients with T4 ultra-low rectal cancer