Study of Iron Accumulation Measured in MRI in Non-pathological Aging (FER-IRM)

University Hospital, Lille

Status: Enrolling

Conditions: Healthy Aging

Study type: Observational

Funder types: Other

Identifiers

NCT04659824

2020-A00491-38 (Other Identifier)

2019_24

Details and patient eligibility

About

To study the correlation between the iron load in brain, measured in MRI, and the age of healthy subjects Secondary objectives are to study the correlations between the iron load in cortical brain regions and (i) the cognitive performances, (ii) markers of aging (MRI, EEG, OCT, biology),and (iii) demographical factors involved in iron load.

Enrollment: 190 estimated patients

Sex: All

Ages: 18 to 95 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Men or women between 18 and 95 years old
• French speaker with capability to understand the instructions
• Health insurance

Exclusion criteria

• Pregnancy
• minor subject
• no informed consent agreement
• subject enrolled in pharmaceutic study or exclusion period
• MRI contra-indications
• Neurological or psychiatric disorders
• MOCA < 26
• Psychotropic drugs
• More than 3 MRI exams
• More than 1 neuropsychological assessment (same cognitive tests) in the last 12 months
• Unable to follow the entire protocol according to the investigator

Trial design

190 participants in 1 patient group

Healthy