Study of Medication and Placebo Response in Major Depression

University of California, Los Angeles (UCLA)

Status and phase: Completed; Phase 4

Conditions: Depressive Disorder, Major

Treatments: Drug: sertraline (Zoloft)

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT00229476

04012549

H6U-US-X002

03-08-033

Details and patient eligibility

About

The primary purpose of the research study is to use recordings of brain electrical activity (through electroencephalogram, or EEG) and symptom measurements to determine whether patients are likely to show a response to medication or placebo treatment during a treatment trial for depression.

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Clinical Diagnosis of Unipolar Major Depression

Exclusion criteria

• Substance Abuse, Psychotic Disorder, History of Severe Head Trauma

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind