Study of Metformin Overdose (METINFO)

Central Hospital, Nancy, France

Status: Unknown

Conditions: Metformin Associated Lactic Acidosis

Treatments: Drug: Metformin

Study type: Observational

Funder types: Other

Identifiers

NCT04762966

2021PI020

Details and patient eligibility

About

The objective of the METINFO study is an observational single-center retrospective and descriptive study. The main objective is to estimate the real mortality rate associated to a Metformin overdose. Second objectives are to estimate the real hospitalization rate related to metformin overdose and to identify the risk factors of a metformin overdose and especially the potential correlation between metformin blood concentration and overdose severity.

Enrollment: 50 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Adult patients benifiting of a metformin blood concentration determination in the period ranging from the 1st of July 2019 and the 1st of July 2021.

Exclusion Criteria: None.

Trial design

50 participants in 2 patient groups

Therapeutic

Description:

Patients with metformin blood concentration in the therapeutic ranges.

Treatment:

Drug: Metformin

Supratherapeutic

Description:

Patients with metformin blood concentration above the therapeutic ranges.

Treatment:

Drug: Metformin