Study of Microbiota in Bile From Patients With Common Bile Duct Stone During ERCP

Shanghai Jiao Tong University

Status: Completed

Conditions: Cholangiopancreatography, Endoscopic Retrograde; Microbial Colonization; Common Bile Duct Calculi

Study type: Observational

Funder types: Other

Identifiers

NCT03490383

CBD stone and microbiota

Details and patient eligibility

About

In this study, investigators will investigate the microbiota of bile in common bile duct stone participants. Three key questions are of concern. The first one is whether there is bacteriria in bile in participants without common bile duct stone. The second one is whether the microbiota of bile is similar with that of gut mucosa in common bile duct stone participants. The third one is whether the bacteria in bile of common bile participants with intact papillar is the same as that of participants underwent sphinctomy.

Enrollment: 60 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• CBD tumor or CBD calculi

Exclusion criteria

• contraindication for ERCP

Trial design

60 participants in 3 patient groups

patients without CBD calculi

Description:

patients without CBD calculi

CBD calculi without ERCP history

Description:

patients with CBD calculi without ERCP history

CBD calculi with ERCP history

Description:

patients with CBD calculi and ERCP history