Study of Naltrexone for Methamphetamine Addiction

California Pacific Medical Center Research Institute

Status and phase: Completed; Phase 2

Conditions: Methamphetamine Dependence

Treatments: Drug: Naltrexone

Study type: Interventional

Funder types: Other

Identifiers

NCT00984360

1R01DA027161-01

Details and patient eligibility

About

The purpose of this study is to determine whether methamphetamine-dependent individuals will use less methamphetamine when treated with naltrexone. The study will also investigate whether individuals with the mu opioid receptor gene variant A118G will use less methamphetamine than individuals without A118G.

Enrollment: 22 patients

Sex: All

Ages: 18 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Age between 18 and 50 years
• Patient is agreeable to conditions of study and signs consent form

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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22 participants in 2 patient groups

A118G

Experimental group

Treatment:

Drug: Naltrexone

Wild-type

Experimental group

Treatment:

Drug: Naltrexone