Study of Neutrophils and Circulating Platelets in Correlation With the Activity of T Lymphocytes in Patients With NAFLD (Nonalcoholic Fatty Liver Disease)

University of L'Aquila

Status: Unknown

Conditions: NAFLD- Non Alcoholic Fatty Liver Disease

Treatments: Diagnostic Test: Data collection

Study type: Observational

Funder types: Other

Identifiers

NCT05358496

31869

Details and patient eligibility

About

The aim of the study is to define the relationship between neutrophils, platelets and the activity of T lymphocytes in patients with NAFLD (nonalcoholic fatty liver disease).

This study may predict, in the course of hepatic steatosis, specific phenotypic patterns expressed by PMNs and circulating platelets to evaluate their role in disease progression.

Enrollment: 80 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients over 18
• No alcoholic abuse
• Hepatic steatosis diagnosticated by abdominal ultrasound
• Negative hepatitis B and C tests
• No history of hepatic cirrhosis

Exclusion criteria

• Under 18
• History of alcoholic abuse
• Positive serology for hepatitis B or C
• History of hepatic cirrhosis

Trial design

80 participants in 2 patient groups

NAFLD cohort

Treatment:

Diagnostic Test: Data collection

Validation cohort

Treatment:

Diagnostic Test: Data collection