Study of Nutrition and Exercise in Adults Hospitalized for Treatment of Acute Lymphoblastic Leukemia (ALL) (NEOMA ALL)

The University of Chicago

Status: Enrolling

Conditions: B-ALL; Philadelphia Chromosome Negative; B Cell Acute Lymphoblastic Leukemia (B-ALL)

Treatments: Behavioral: Nutrition Intervention; Behavioral: Exercise intervention

Study type: Interventional

Funder types: Other

Identifiers

NCT06785324

IRB24-1500

Details and patient eligibility

About

This clinical trial aims to assess the effect of nutrition and exercise on muscle and adiposity in adults with Philadelphia Chromosome (Ph) Negative B-ALL undergoing inpatient induction therapy.

Participants will take part in 2 different interventions:

• Nutrition Intervention
• Physical Exercise Intervention

All subjects will be provided with a wearable electronic activity monitor (FitBit®) to assist in recording activity levels in minutes of activity.

Enrollment: 20 estimated patients

Sex: All

Ages: 18 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• New Diagnosis of Philadelphia Chromosome Negative B-ALL
• Receiving intensive pediatric-inspired induction chemotherapy

Exclusion criteria

• BMI ≤18.5 kg/m2 at time of diagnosis
• Unable to comply with both the recommended diet and exercise regimen as deemed by the research or treatment team
• Pregnant

Trial design

Primary purpose: Supportive Care

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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20 participants in 1 patient group

Nutrition and Exercise interventions

Experimental group

Description:

Participants will receive an exercise and nutrition (diet) intervention while hospitalized for routine treatment for their ALL.

Treatment:

Behavioral: Exercise intervention

Behavioral: Nutrition Intervention