Study of Photodynamic Therapy (PDT) in Patients With Central Serous Chorioretinopathy (CSC)

Peking University

Status and phase: Completed; Phase 4

Conditions: Central Serous Chorioretinopathy

Treatments: Procedure: PDT

Study type: Interventional

Funder types: Other

Identifiers

NCT01574430

PDTCSC-CHINA

Details and patient eligibility

About

The purpose of this study is to determine the safety and efficacy of PDT at 30% verteporfin dose in the treatment of CSC.

Enrollment: 131 estimated patients

Sex: All

Ages: 18 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients with CSC
• patients signed the ICF
• patients with course of CSC less than 6 months
• patients did not undertake any treatment for CSC

Exclusion criteria

• patients with porphyria
• patients allergic to verteporfin
• pregnant or nursing women
• poor patients compliance
• sever liver dysfunction
• dioptric media opacities which make it difficult to exam fundus

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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131 participants in 2 patient groups

50% dose PDT

Active Comparator group

Description:

patients in this group was given 50% verteporfin dose PDT

Treatment:

Procedure: PDT

30% dose PDT

Experimental group

Description:

patients in this group was given 30% verteporfin dose PDT

Treatment:

Procedure: PDT